Research

Neuroscience Clinical Research

Capital Institute for Neurosciences participates in, and develops, numerous research studies and clinical trials. The goal is to help provide greater understanding of neurological diseases, develop new methods to detect and diagnose those diseases, and focus on innovative treatments that are not broadly available to patients.

Clinical trials offer patients some of the very latest in care while giving physicians and researchers the opportunity to study the safety and effectiveness of new treatments. Participation is voluntary.

Our experienced neurologists and neurosurgeons, and research nurses, carefully review study criteria, potential benefits, risks, and other considerations with eligible patients for enrollment into a clinical study. Once enrolled, our clinical research staff carefully monitors patients throughout the research trial and is available to answer questions.

To learn more about our ongoing trials available at Capital Health, please e-mail [email protected].

Stroke

Pharyngeal Electrical Stimulation Evaluation for Dysphagia after Stroke (PhEED)

PI: Dr. H. Christian Schumacher
Sub-I: Drs. Kevin McGuigan and Madhu Jain - St. Lawrence Rehabilitation
Sponsor: Phagenesis

Tenecteplase in Stroke Patients Between 4 and 24 Hours (TIMELESS)

PI: Dr. Dustin Rochestie
Co-I: Dr. Christian Schumacher
Sponsor: Genentech

 

Neuro-Oncology/Brain Tumors

3D-PREDICT REGISTRY: 3D Prediction of patient-specific response using ex vivo interrogation of live cells from tumors

Study Information: NCT03561207
Sponsor: KIYATEC, Inc.
Principal Investigator: Navid Redjal, MD, FAANS, Neurosurgeon
Contact: Dr. Neena Shetty, Clinical Research Coordinator at [email protected] or 609-394-4024

Observation or radiation therapy in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery

Study Information: NCT03180268
Sponsor: National Clinical Trials Network, NCI through collaborative groups
Principal Investigator: Navid Redjal, MD, FAANS, Neurosurgeon
Contact: Dr. Neena Shetty, Clinical Research Coordinator at [email protected] or 609-394-4024

Molecular and biochemical characterization of malignant and metastatic brain tumors

Study Information: NCT N/A
Sponsor: Capital Health System, Inc. in collaboration with Princeton University and Rutgers University
Principal Investigator: Navid Redjal, MD, FAANS, Neurosurgeon
Contact: Dr. Neena Shetty, Clinical Research Coordinator at [email protected] or 609-394-4024

Genomically-guided treatment trial in brain metastasis

Study Information: NCT03994796
Sponsor: National Clinical Trials Network, NCI through collaborative groups
Principal Investigator: Dr. Neel Gandhi, Medical Oncologist
Contact: Dr. Neena Shetty, Clinical Research Coordinator at [email protected] or 609-394-4024

Assessing quality of life in adult neuro-oncology patients after Cyberknife or WBRT (Whole Brain Radiation Therapy), a prospective registry

Study Information: NCT N/A
Sponsor: Capital Health System, Inc.
Principal Investigator: Navid Redjal, MD, FAANS, Neurosurgeon
Contact: Dr. Neena Shetty, Clinical Research Coordinator at [email protected] or 609-394-4024

The use of the ketogenic diet as an adjuvant to treatment of glioblastome multiforme

Study Information: NCT N/A
Sponsor: Capital Health System, Inc.
Principal Investigator: Navid Redjal, MD, FAANS, Neurosurgeon
Contact: Dr. Neena Shetty, Clinical Research Coordinator at [email protected] or 609-394-4024

Testing the Use of the Immunotherapy Drugs, Ipilimumab and Nivolumab, Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

Study Information: NCT04396860
Sponsor: National Cancer Institute (NCI)
Principal Investigator: Neel Gandhi, MD
Contact: Dr. Neena Shetty, Clinical Research Coordinator at [email protected] or 609-394-4024

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioblastoma With Elevated Mutational Burden

Study Information: NCT04145115
Sponsor: National Cancer Institute (NCI)
Principal Investigator: Neel Gandhi, MD
Contact: Dr. Neena Shetty, Clinical Research Coordinator at [email protected] or 609-394-4024

 

Spine

Outcomes and Quality of Life after Spine Surgery

Narrative: Assessment of quality of life outcomes and comparison to national standards in patients after selected spine surgery.

PI: Dr. Lee Buono
Sponsor: Capital Health

 

Other

Retrospective Collection of Non-Contrast Head CT images for Clinical Evaluation of MaxQ-AI Accipio Family Software

The primary objective of this retrospective image collection study is to obtain study image data in order to establish and document ground truth for each subject. This study will create a library of image data that will be used for retrospective reader studies and standalone testing.

PI: Dr. Chirag Shukla
Co-I: Dr. Ajay Choudri
Sponsor: MaxQ-IA